Digestive Disease Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue/A30, Cleveland, OH 44195, USA.
J Gastrointest Surg. 2010 Jun;14(6):993-7. doi: 10.1007/s11605-010-1194-y.
The study aim is to review the prevalence, management, and outcomes for patients diagnosed with ileal pouch prolapse after restorative proctocolectomy.
Patients were identified retrospectively from a prospectively maintained pouch database. Parameters analyzed included presenting symptoms, indications for pouch surgery, type of ileal pouch-anal anastomosis, treatment modalities, and outcomes.
Of 3,176 patients who underwent ileal pouch surgery, 11 were diagnosed with pouch prolapse (0.3%). Seven had full-thickness prolapse and four mucosal prolapse. Six were male, and five were female. Indication for index surgery was ulcerative colitis (nine patients), familial adenomatous polyposis (one patient), and colonic inertia (one patient). Median age at pouch prolapse was 34 years. Median time from index surgery to prolapse diagnosis was 2 years. Two patients with mucosal prolapse responded to conservative management; two required mucosal excisions. An abdominal approach was successful in four out of seven patients with full thickness prolapse. The three failures subsequently underwent continent ileostomy formation and prompted us to add biological mesh to future pouchpexy repairs.
Pouch prolapse is rare, and there are no obvious predisposing factors. Mucosal prolapse may be treated by stool bulking or a local perineal procedure. Full thickness prolapse requires definitive surgery and is associated with risk of pouch loss.
本研究旨在回顾因直肠结肠切除术后回肠袋脱垂而接受治疗的患者的患病率、处理方法和结局。
从前瞻性维持的回肠袋数据库中回顾性地确定患者。分析的参数包括首发症状、回肠袋手术指征、回肠直肠吻合术类型、治疗方式和结局。
在 3176 例行回肠袋手术的患者中,有 11 例被诊断为回肠袋脱垂(0.3%)。其中 7 例为全层脱垂,4 例为黏膜脱垂。6 例为男性,5 例为女性。指数手术的指征为溃疡性结肠炎(9 例)、家族性腺瘤性息肉病(1 例)和结肠无力(1 例)。回肠袋脱垂的中位年龄为 34 岁。从指数手术到脱垂诊断的中位时间为 2 年。2 例黏膜脱垂患者对保守治疗有反应;2 例需要黏膜切除术。7 例全层脱垂患者中有 4 例通过腹部手术成功,3 例手术失败的患者随后行 continent ileostomy 造口术,并促使我们在未来的回肠袋固定修复术中添加生物补片。
回肠袋脱垂罕见,无明显的诱发因素。黏膜脱垂可通过粪便膨体或局部会阴手术治疗。全层脱垂需要明确的手术,且有回肠袋丢失的风险。