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实验性内毒素血症中非甲状腺疾病综合征发展的形态功能分析

Morphofunctional analysis of development of nonthyroid disease syndrome in experimental endotoxicosis.

作者信息

Yaglova N V

机构信息

Institute of Human Morphology, the Russian Academy of Medical Sciences, Moscow, Russia.

出版信息

Bull Exp Biol Med. 2009 Nov;148(5):829-33. doi: 10.1007/s10517-010-0828-0.

Abstract

The development of the nonthyroid disease syndrome in acute endotoxicosis involves mechanisms related to polarization of the immune response by the Th1 type. Thyroid status of rats with pronounced and weak polarization of the immune response was evaluated. Morphofunctional changes in the thyroid gland in animals with the central and peripheral mechanisms of the development and regression of the nonthyroid disease syndrome were detected.

摘要

急性内毒素血症中非甲状腺疾病综合征的发展涉及与Th1型免疫反应极化相关的机制。评估了免疫反应极化明显和微弱的大鼠的甲状腺状态。检测了非甲状腺疾病综合征发生和消退的中枢和外周机制的动物甲状腺的形态功能变化。

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