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腹腔镜胃旁路术后胃空肠吻合口狭窄的内镜扩张。初始失败的预测因素。

Endoscopic dilation of gastrojejunal anastomotic strictures after laparoscopic gastric bypass. Predictors of initial failure.

机构信息

Endoscopy Unit, Centro Médico Teknon, Barcelona, Spain.

出版信息

Obes Surg. 2011 Jan;21(1):36-41. doi: 10.1007/s11695-010-0154-7.

Abstract

BACKGROUND AND AIMS

Laparoscopic Roux-en-Y gastric bypass (LRYGB) is the most frequent technique performed in bariatric surgery. Gastrojejunal anastomotic stricture is one of the most common postoperative complications. The aims of this study were to evaluate the efficacy and safety of endoscopic balloon dilation in the treatment of the gastrojejunal anastomotic strictures after LRYGB and to look for predicting factors that would indicate the need of repeated dilations.

METHODS

We included all patients with morbid obesity who underwent a LRYGB at our institution between January 2002 and July 2007. All patients who developed symptoms compatible with stricture of the gastrojejunostomy were referred to upper gastrointestinal endoscopy and underwent endoscopic balloon dilation.

RESULTS

One hundred and five out of the 1,330 patients (7.8%) developed an anastomotic stricture. The mean time to diagnosis was 3 months after the surgery. The mean diameter of the stricture was 5 mm. Sixty out of the 105 patients required only one dilation (57%), 29 required two dilations (27,6%), 13 required three dilations, and 3 patients underwent a fourth dilation. Clinical success was achieved in 100% of the cases, with an average of 1.6 dilations. The statistical analysis showed that only the time from surgery to stricture formation (p = 0.007) and the diameter achieved at the first dilation (p = 0.015) had statistical significance as predictors of the need of one or more dilations.

CONCLUSIONS

Endoscopic balloon dilation is a safe and effective method. Most of the patients are successfully managed with one or two dilations. The longer time from surgery to the appearance of symptoms ant the largest diameter achieved at the first dilation are the only predicting factors of success with only one dilation.

摘要

背景与目的

腹腔镜 Roux-en-Y 胃旁路术(LRYGB)是减重手术中最常见的技术。胃空肠吻合口狭窄是最常见的术后并发症之一。本研究旨在评估内镜球囊扩张治疗 LRYGB 后胃空肠吻合口狭窄的疗效和安全性,并寻找预示需要多次扩张的因素。

方法

我们纳入了 2002 年 1 月至 2007 年 7 月在我们机构接受 LRYGB 的所有病态肥胖患者。所有出现符合胃空肠吻合口狭窄症状的患者均被转诊至上消化道内镜,并接受内镜球囊扩张。

结果

1330 例患者中有 105 例(7.8%)发生吻合口狭窄。诊断时间平均为手术后 3 个月。狭窄的平均直径为 5 毫米。105 例患者中有 60 例仅需扩张一次(57%),29 例需扩张两次(27.6%),13 例需扩张三次,3 例需扩张四次。所有病例均达到临床成功,平均扩张 1.6 次。统计分析显示,仅手术至狭窄形成时间(p=0.007)和首次扩张时达到的直径(p=0.015)具有统计学意义,是需要一次或多次扩张的预测因素。

结论

内镜球囊扩张是一种安全有效的方法。大多数患者通过一次或两次扩张即可成功治疗。手术至症状出现时间越长,以及首次扩张时达到的最大直径越大,是仅需一次扩张即可成功的唯一预测因素。

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