Khan Sardar U, Kenefick Cyril, O'Leary Gerard, Lucey James J
Department of Otorhinolaryngology-Head and Neck Surgery, South Infirmary-Victoria University Hospital, Cork, Ireland.
Ear Nose Throat J. 2010 Apr;89(4):E4-5.
We describe the case of a 57-year-old man who was referred to us with persistent sore throat, dysphagia, and enlarged tonsils. He had not responded to earlier treatment with antibiotic therapy and other routine measures. In view of the persistent nature of the patient's symptoms and the tonsillar hypertrophy, we decided to perform a tonsillectomy and to send the excised specimens for pathologic analysis. Histologic evaluation identified non-Hodgkin lymphoma in both tonsils. The patient was treated with postoperative chemo- and radiotherapy, and he was free of symptoms during 18 months of follow-up. To the best of our knowledge, only 4 cases of bilateral non-Hodgkin lymphoma of the tonsils have been reported in the English-language literature. We also discuss the importance of histologic analysis of excised tonsil tissue in selected cases.
我们描述了一名57岁男性的病例,他因持续咽痛、吞咽困难和扁桃体肿大被转诊至我院。他对早期的抗生素治疗和其他常规措施没有反应。鉴于患者症状的持续性和扁桃体肥大,我们决定进行扁桃体切除术,并将切除的标本送去做病理分析。组织学评估在双侧扁桃体中均发现了非霍奇金淋巴瘤。该患者接受了术后化疗和放疗,在18个月的随访期间无症状。据我们所知,英文文献中仅报道了4例双侧扁桃体非霍奇金淋巴瘤病例。我们还讨论了在特定病例中对切除的扁桃体组织进行组织学分析的重要性。