Mazokopakis Elias E, Syros Periklis K, Starakis Ioannis K
Department of Internal Medicine, Naval Hospital of Crete, 73 200 Chania, Crete, Greece.
Cardiovasc Hematol Disord Drug Targets. 2010 Jun;10(2):84-6. doi: 10.2174/187152910791292484.
The term nonbacterial thrombotic endocarditis (NBTE), or marantic endocarditis, refers to a spectrum of lesions ranging from microscopic aggregates of platelets to large vegetations on previously undamaged heart valves (most often aortic and mitral) in the absence of a bloodstream bacterial infection. NBTE is a rare condition often associated with hypercoagulable states or advanced malignancy such as adenocarcinomas. In this article, the pathogenesis, incidence, clinical manifestations, diagnosis, and management of NBTE in cancer patients are reviewed.
非细菌性血栓性心内膜炎（NBTE），或称消耗性心内膜炎，是指在没有血流细菌感染的情况下，从血小板的微观聚集体到先前未受损心脏瓣膜（最常见的是主动脉瓣和二尖瓣）上的大赘生物等一系列病变。NBTE是一种罕见疾病，常与高凝状态或晚期恶性肿瘤如腺癌相关。本文对癌症患者中NBTE的发病机制、发病率、临床表现、诊断及管理进行综述。
