Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Zürich, Switzerland.
Arch Oral Biol. 2010 Jun;55(6):441-6. doi: 10.1016/j.archoralbio.2010.03.016.
To investigate the effect of cerium chloride, cerium chloride/fluoride and fluoride application on calcium release during erosion of treated dentine.
Forty dentine samples were prepared from human premolars and randomly assigned to four groups (1-4). Samples were treated twice a day for 5 days, 30s each, with the following solutions: group 1 placebo, group 2 fluoride (Elmex fluid), group 3 cerium chloride and group 4 combined fluoride and cerium chloride. For the determination of acid resistance, the samples were consecutively eroded six times for 5 min with lactic acid (pH 3.0) and the calcium release in the acid was determined. Furthermore, six additional samples per group were prepared and used for EDS analysis. SEM pictures of these samples of each group were also captured.
Samples of group 1 presented the highest calcium release when compared with the samples of groups 2-4. The highest acid resistance was observed for group 2. Calcium release in group 3 was similar to that of group 4 for the first two erosive attacks, after which calcium release in group 4 was lower than that of group 3. Generally, the SEM pictures showed a surface coating for groups 2-4. No deposits were observed in group 1.
Although fluoride showed the best protective effect, cerium chloride was also able to reduce the acid susceptibility of dentine significantly, which merits further investigation.
研究氯化铈、氯化铈/氟化物和氟化物应用对脱矿牙本质钙释放的影响。
从人前磨牙中制备 40 个牙本质样本，随机分为四组（1-4）。样本每天处理两次，每次 30 秒，使用以下溶液：组 1 安慰剂，组 2 氟化物（Elmex 液），组 3 氯化铈，组 4 氟化物和氯化铈的混合物。为了测定抗酸性，将样本用乳酸（pH3.0）连续侵蚀 6 次，每次 5 分钟，并测定酸中的钙释放量。此外，每组还另外准备了 6 个样本用于 EDS 分析。还拍摄了每组这些样本的 SEM 图片。
与组 2-4 相比，组 1 的样本释放的钙最多。组 2 的抗酸性最高。在前两次侵蚀攻击中，组 3 的钙释放与组 4 相似，之后组 4 的钙释放低于组 3。一般来说，SEM 图片显示组 2-4 表面有涂层。组 1 中没有观察到沉积物。
尽管氟化物显示出最佳的保护效果，但氯化铈也能显著降低牙本质的酸敏感性，值得进一步研究。
