Department of Pathology, University Medicine, Robert-Koch-Strasse 40, D-37099 Göttingen, Germany.
Pathol Res Pract. 2010 Jul 15;206(7):519-21. doi: 10.1016/j.prp.2010.02.006.
Krukenberg tumor is a well-known ovarian metastasis, usually of gastric signet ring cell carcinoma in female patients. Although gastric carcinoma is more frequent in men, to our knowledge, only few cases of counterpart testicular metastases have been described as yet. We report a 64-year-old patient who complained of right testicular pain. Right-sided orchiectomy was performed, and metastatic signet ring cell carcinoma of spermatic cord and testis was diagnosed through histological examination and immunohistochemistry. The following stomach biopsy confirmed the primary signet ring cell carcinoma in the stomach. This extremely rare form of metastatic dissemination resembles the Krukenberg tumor of ovaries. Immunohistochemical staining plays an important role in the differential diagnosis of spermatic cord enlargement.
库肯勃瘤是一种著名的卵巢转移瘤，通常来源于女性患者的胃印戒细胞癌。尽管胃癌在男性中更为常见，但据我们所知，目前仅少数病例描述了相应的睾丸转移。我们报告了一例 64 岁男性患者，其主诉为右侧睾丸疼痛。行右侧睾丸切除术，组织学检查和免疫组织化学检查诊断为精索和睾丸转移性印戒细胞癌。随后的胃活检证实了胃内原发性印戒细胞癌。这种极其罕见的转移播散形式类似于卵巢的库肯勃瘤。免疫组织化学染色在精索增粗的鉴别诊断中发挥着重要作用。
