两种小鼠品系中嗜异性白血病病毒诱导位点的遗传图谱分析。
Genetic mapping of xenotropic leukemia virus-inducing loci in two mouse strains.
作者信息
Kozak C, Rowe W P
出版信息
Science. 1978 Mar 31;199(4336):1448-9. doi: 10.1126/science.204014.
PMID:204014
Abstract
In genetic studies of C57BL/10 and BALB/c mice, inducibility of xenotropic murine leukemia virus from tissue cultures by treatment with 5-iododeoxyuridine shows single gene segregation ratios. In both strains, the virus-inducing loci are on chromosome 1, linked to the Dip-1/isozyme locus, but the two may not be at allelic sites.
摘要
在对C57BL/10和BALB/c小鼠的遗传学研究中，用5-碘脱氧尿苷处理组织培养物诱导嗜异性小鼠白血病病毒的能力呈现单基因分离比例。在这两个品系中，病毒诱导位点都位于1号染色体上，与Dip-1/同工酶位点连锁，但两者可能不在等位基因位点。
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