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[膝关节炎患者滑液中蛋白质谱与各类免疫球蛋白的相关性]

[An association of the protein spectrum and various immunoglobulin classes in synovial fluid in gonarthrosis].

作者信息

Luneva S N, Matveeva E L, Chepeleva M V, Gasanova A G, Spirkina E S

出版信息

Klin Lab Diagn. 2010 Feb(2):21-3.

Abstract

Synovial fluid from patients with gonarthrosis was examined using biochemical and immunological studies; the levels of total protein, protein fractions, and immunoglobulins A, M, and G were measured. In a joint osteoarthrotic process, the patients' synovial fluid showed a significant increase in the levels of immunoglobulins of all classes and total protein, a change in the distribution of protein fractions, and a close correlation between IgM and a protein beta-globulin fraction.

摘要

采用生化和免疫学研究方法对膝骨关节炎患者的滑液进行检测;测定了总蛋白、蛋白组分以及免疫球蛋白A、M和G的水平。在关节骨关节炎进程中,患者的滑液显示出所有类别免疫球蛋白和总蛋白水平显著升高、蛋白组分分布改变以及IgM与一种β球蛋白组分之间存在密切相关性。

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