Thomas B J
Department of Physics, Queensland University of Technology, Brisbane, Australia.
Environ Health Perspect. 1991 Feb;91:39-43. doi: 10.1289/ehp.919139.
Several groups have reported the development of systems, based on the principle of X-ray fluorescence, for the in vivo measurement of bone lead concentrations. These systems have used the detection of either the characteristic L or K X-rays resulting from excitation by a suitable photon source. This paper examines design issues related to the development of these systems. These design issues are, in most instances, a result of consideration of the physical principles involved, and hence there are many features common to the systems developed by the individual groups. Design issues discussed in this paper include the selection of the site for measurement, source-sample-detector configuration, and collimation. Specific examples from published work are used to demonstrate the relevant features.
有几个研究小组报告了基于X射线荧光原理开发的用于体内测量骨铅浓度的系统。这些系统利用合适的光子源激发产生的特征L或K X射线进行检测。本文探讨了与这些系统开发相关的设计问题。在大多数情况下，这些设计问题是考虑相关物理原理的结果，因此各个研究小组开发的系统有许多共同特征。本文讨论的设计问题包括测量部位的选择、源-样品-探测器配置和准直。文中引用已发表研究工作中的具体例子来说明相关特征。
