Perondi R, Gregorini L, Pomidossi G, Saino A, Alessio P, Zanchetti A, Mancia G
Instituto di Clinica Medica Generale e Terapia Medica, Università di Milano, Italy.
Eur Heart J. 1991 Mar;12(3):363-7. doi: 10.1093/oxfordjournals.eurheartj.a059903.
Although intravenous digital subtraction ventriculography (IDSV) is increasingly used to estimate end-diastolic left ventricular volume (EDV), end-systolic left ventricular volume (ESV) and left ventricular ejection fraction (EF), its ability to reproduce the precise estimates provided by left ventricle cineangiography (LVCA) and its role in clinical cardiology have not been unequivocally established. In 32 patients subjected to cardiac catheterization for a variety of cardiac disorders and a normal or reduced left ventricular function the EDV, ESV and EF provided by a 30 degrees right anterior oblique LVCA were compared with those provided by a 30 degrees right anterior oblique IDSV. The mean EDV, ESV and EF obtained by IDSV in the 32 patients were superimposable on those obtained by LVCA. The individual EDV, ESV and EF values provided by the two methods were all related in a close linear fashion. For EF the correlation coefficient was 0.98 and the 90% confidence interval of the mean difference between the two series of values was +/- 6.1%, i.e. +/- 10% error compared to the mean EF provided by LVCA. Thus IDSV is a reliable and not too invasive method for estimating left ventricle volumes and ejection fraction. It might provide serial estimations with a better assessment of the evolution of a patient's disease and the effect of treatment.
尽管静脉数字减影心室造影（IDSV）越来越多地用于估计舒张末期左心室容积（EDV）、收缩末期左心室容积（ESV）和左心室射血分数（EF），但其再现左心室电影血管造影（LVCA）所提供的精确估计值的能力及其在临床心脏病学中的作用尚未得到明确证实。在32例因各种心脏疾病接受心导管检查且左心室功能正常或降低的患者中，比较了30度右前斜位LVCA所提供的EDV、ESV和EF与30度右前斜位IDSV所提供的结果。IDSV在这32例患者中获得的平均EDV、ESV和EF与LVCA获得的结果重叠。两种方法所提供的个体EDV、ESV和EF值均呈密切的线性关系。对于EF，相关系数为0.98，两组值之间平均差异的90%置信区间为±6.1%，即与LVCA提供的平均EF相比误差为±10%。因此，IDSV是一种可靠且侵入性较小的估计左心室容积和射血分数的方法。它可能提供系列估计值，以便更好地评估患者疾病的进展和治疗效果。
