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慢性心肌梗死患者中可诱导性室上性快速性心律失常的发生率及意义

Incidence and significance of inducible supraventricular tachyarrhythmias in patients with chronic myocardial infarction.

作者信息

Brembilla-Perrot B, de la Chaise A T, Lessa de Souza M, Bailly L

机构信息

Cardiologie, Chu of Brabois, Vandoeuvre, France.

出版信息

Eur Heart J. 1991 Mar;12(3):401-4. doi: 10.1093/oxfordjournals.eurheartj.a059908.

DOI:10.1093/oxfordjournals.eurheartj.a059908
PMID:2040323
Abstract

In order to evaluate the incidence and significance of inducible supra-ventricular (SVTA) in patients with chronic myocardial infarction (MI), the results of systematic programmed atrial stimulation were compared in two groups of patients: 150 patients (group I) without MI or underlying heart disease, studied for syncope or conduction disturbances, 296 patients (group II) studied after an acute Mi (greater than 1 month). None of them had spontaneous SVTA, and 24-h Holter monitoring showed no SVTA. The atrial stimulation programme used one and two extra stimuli delivered during sinus rhythm and atrial pacing (600 ms and 10% less than the sinus cycle length). A sustained (S) (greater than 30 s) supraventricular tachycardia (SVT) (atrial flutter, fibrillation, tachycardia) was induced in 17 patients in group I (11%) and in 120 patients in group II (40.5%). In group II inducible SVTA could not be correlated with the occurrence of a SVT during acute MI, the location of MI, the value of LV ejection fraction (EF), the incidence of inducible sustained ventricular tachycardia (VT), or fibrillation (VF). However, inducible SVTA could be correlated with a significantly shorter effective atrial refractory period (197 +/- 23 ms vs 220 +/- 35 ms, P less than 0.001) and a shorter retrograde block cycle length (518 +/- 215 vs 585 +/- 215 ms, P less than 0.03). The patients in group II were followed-up for at least 6 months; 12 of them developed sustained episodes of supraventricular tachycardia; 11 of them had inducible SVTA (P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为评估慢性心肌梗死(MI)患者中可诱导性室上性心动过速(SVTA)的发生率及意义,对两组患者的系统性程控心房刺激结果进行了比较:150例无MI或潜在心脏病的患者(I组),因晕厥或传导障碍接受研究;296例急性MI(超过1个月)后接受研究的患者(II组)。两组患者均无自发性SVTA,24小时动态心电图监测也未发现SVTA。心房刺激程序在窦性心律和心房起搏时施加一个和两个额外刺激(600毫秒,比窦性周期长度短10%)。I组17例患者(11%)和II组120例患者(40.5%)诱发出持续性(S)(超过30秒)室上性心动过速(SVT)(心房扑动、颤动、心动过速)。在II组中,可诱导性SVTA与急性MI期间SVT的发生、MI的部位、左心室射血分数(EF)值、可诱导性持续性室性心动过速(VT)或颤动(VF)的发生率均无相关性。然而,可诱导性SVTA与明显更短的有效心房不应期(197±23毫秒对220±35毫秒,P<0.001)和更短的逆向传导阻滞周期长度(518±215对585±215毫秒,P<0.03)相关。II组患者随访至少6个月;其中12例发生持续性室上性心动过速发作;11例有可诱导性SVTA(P<0.001)。(摘要截选至250字)

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