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急性心肌梗死后室上性快速心律失常与左心室功能障碍之间的关系。

The relation between supraventricular tachyarrhythmias and left ventricular dysfunction after acute myocardial infarction.

作者信息

Zoni Berisso M, Carratino L, Ferroni A, De Caro E, Mela G S, Vecchio C

机构信息

Divisione di Cardiologia, Ospedali Galliesa, Genova.

出版信息

Acta Cardiol. 1988;43(6):689-701.

PMID:3266415
Abstract

The clinical characteristics of supraventricular tachyarrhythmias (SVTA) and their relation to left ventricular dysfunction were assessed in 208 consecutive patients with recent myocardial infarction. Arrhythmias were quantified on hospital discharge by 24 hour electrocardiographic recording. All the variables were evaluated between the second and the fourth week after infarction. SVTA occurred in 113 (54%) patients: Supraventricular premature beats (SVPB) in 49 (24%), frequent or repetitive SVPB in 37 (18%), atrial or junctional tachycardia in 23 (11%), atrial flutter or fibrillation in 4 (2%). Most of these arrhythmias occurred in the absence of symptoms, and the most complex forms were always selflimiting. No relation was found among the presence of different forms of SVTA and sex, coronary risk factors, previous history of ischemic heart disease, type or site of acute myocardial infarction, NYHA functional class. Age, left atrial dimension (LAD), cardio-thoracic ratio (CTR) and left ventricular ejection fraction (LVEF) at rest differed significantly among three groups of patients: those without SVTA, those with SVPB less than 100 per hour and those with frequent-repetitive SVPB or atrial-junctional tachycardia. The more SVTA complexity, the worse LAD, CTR, LVEF and the higher the age. Multivariate discriminant analysis showed that CTR was directly and LVEF inversely related to the occurrence of SVPB less than 100 per hour, while the presence of frequent-repetitive SVPB or supraventricular tachycardia was closely related to increasing age, LAD, CTR and decreasing LVEF. Patients with atrial fibrillation always showed the worst values of LAD, CTR, LVEF and age. The results of the present study show that different types of SVTA occurring at discharge from hospital after myocardial infarction are clinically benign, but always suggestive of different degrees of left ventricular dysfunction.

摘要

对208例近期发生心肌梗死的连续患者评估了室上性快速心律失常(SVTA)的临床特征及其与左心室功能障碍的关系。心律失常在出院时通过24小时心电图记录进行量化。所有变量在梗死发生后的第二至第四周进行评估。113例(54%)患者发生SVTA:49例(24%)出现室上性早搏(SVPB),37例(18%)出现频发或反复性SVPB,23例(11%)出现房性或交界性心动过速,4例(2%)出现心房扑动或颤动。这些心律失常大多在无症状时发生,最复杂的类型总是自限性的。未发现不同形式的SVTA的存在与性别、冠状动脉危险因素、既往缺血性心脏病史、急性心肌梗死的类型或部位、纽约心脏协会(NYHA)心功能分级之间存在关联。三组患者在年龄、静息时左心房内径(LAD)、心胸比率(CTR)和左心室射血分数(LVEF)方面存在显著差异:无SVTA的患者、每小时SVPB少于100次的患者以及频发-反复性SVPB或房性-交界性心动过速的患者。SVTA越复杂,LAD、CTR、LVEF越差,年龄越高。多变量判别分析显示,CTR与每小时SVPB少于100次的发生呈正相关,LVEF与之呈负相关,而频发-反复性SVPB或室上性心动过速的存在与年龄增加、LAD、CTR升高以及LVEF降低密切相关。心房颤动患者的LAD、CTR、LVEF和年龄值总是最差的。本研究结果表明,心肌梗死后出院时出现的不同类型的SVTA在临床上是良性的,但总是提示不同程度的左心室功能障碍。

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