Paul R, Ylinen S L
Turku University Central Hospital, Department of Nuclear Medicine, Finland.
Eur J Nucl Med. 1991;18(3):222-4. doi: 10.1007/BF02262733.
A patient with alkaptonuria and ochronotic arthrosis was imaged twice with technetium-99m dicarboxypropane diphosphonate (99mTc-DPD)--once during a bout of arthritic knee pain and once when symptom-free. There was a marked accumulation of radioactivity in the large joints. During the episode of arthritis the knee joints had a higher uptake than when the patient was without symptoms. The intervertebral discs showed a high uptake which extended laterally from the axial vertebral column; the finding gave an impression of whiskers, and this "whisker sign" may be characteristic of ochronosis.
一名患有尿黑酸尿症和褐黄病性关节炎的患者用锝-99m二羧丙烷二膦酸盐（99mTc-DPD）进行了两次成像——一次是在膝关节疼痛发作期间，另一次是在无症状时。大关节中有明显的放射性聚集。在关节炎发作期间，膝关节的摄取量高于患者无症状时。椎间盘显示出高摄取，从脊柱轴向外侧延伸；这一发现给人一种胡须的印象，这种“胡须征”可能是褐黄病的特征。
