Quasar Grunwald Iris, Molyneux Andrew, Kühn Anna Luisa, Watson Dave, Byrne James V
Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom.
Vasc Endovascular Surg. 2010 May;44(4):289-93. doi: 10.1177/1538574410363916.
This prospective randomized double-blinded in-vitro study was conducted to determine the relative Packing Density (PD) of the new Deltapaq coil (Micrus Endovascular) as compared to Micrus's conventional filling CHE (Helipaq) and finishing CFS (Ultipaq) coils.
Two physicians independently deployed the coils under fluoroscopy into a 4mm berry shaped glass aneurysm. Each coil tested was a 4mm x 35cm coil specially made for this study. Physicians and observer were blinded as to the type of coil. Five samples per group, per operator, were deployed.
mean PD were 36.6% (Helipaq), 37.9% (Ultipaq) and 40.4% (Deltapaq). Two-sample T-test showed a significantly higher PD of Deltapaq versus Helipaq (p < 0.022).
Higher coil PD and better neck coverage may provide an increased biomechanical stability and may potentially reduce the recanalization rate of aneurysms.
The new Deltapaq coil may have the potential to achieve higher packing densities in the treatment of aneurysms.