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[非产褥期乳腺炎的成功治疗——已成常规还是仍属罕见?]

[Successful therapy of nonpuerperal mastitis--already routine or still a rarity?].

作者信息

Goepel E, Pahnke V G

机构信息

Frauenklinik Universität Hamburg-Eppendorf.

出版信息

Geburtshilfe Frauenheilkd. 1991 Feb;51(2):109-16. doi: 10.1055/s-2007-1023685.

DOI:10.1055/s-2007-1023685
PMID:2040409
Abstract

The data from 102 patients with an average age of 36 +/- 14.4 years, who underwent treatment for nonpuerperal mastitis (NPM) were examined. After a definite diagnosis had been made, the patients were treated with a prolactin inhibitor either on its own, or in combination with antibiotics. In 34.1% of the patients, the abscess was either opened or tumour remnants were exstirpated. 51.9% of the patients acquired the disease between the ages of 18 and 40 years. In 62.7%, it was the first incidence of NPM. 86.3% had a previous history of other mammary disorders, e.g. mastodyny or macromasty. 55.9% were prone to irregular menstruation and 50% showed incidence of disorders of the thyroid gland. The characteristic clinical signs were reddening, infiltration, enlarged lymph nodes and in 37.5% of the patients a primary abscess. 75% of the patients, who underwent thermographic scanning, showed incidence of hot spots and 71.7% of the patients, who underwent a mammography, presented pathological results. 63% of the 54 patients, exclusively treated with antibiotics, showed incidence of abscesses as opposed to only 25% of the 48 patients treated with bromocriptin. In the first group, the overall rate of cure was 29.6% compared to 93.7% among those patients, treated with bromocriptin. An exact anamnesis highlights the pathophysiological mechanisms, that most probably leads to the disease. In 13.7%, a suspected inflammatory mammary carcinoma required a histological investigation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对102例平均年龄为36±14.4岁、接受非产褥期乳腺炎(NPM)治疗的患者的数据进行了检查。确诊后,患者单独或联合使用抗生素接受催乳素抑制剂治疗。34.1%的患者脓肿被切开或切除肿瘤残余。51.9%的患者在18至40岁之间患病。62.7%的患者为首次发生NPM。86.3%的患者既往有其他乳腺疾病史,如乳腺疼痛或巨乳症。55.9%的患者月经不规律,50%的患者有甲状腺疾病史。特征性临床体征为发红、浸润、淋巴结肿大,37.5%的患者有原发性脓肿。75%接受热成像扫描的患者出现热点,71.7%接受乳房X光检查的患者呈现病理结果。仅接受抗生素治疗的54例患者中,63%出现脓肿,而接受溴隐亭治疗的48例患者中只有25%出现脓肿。在第一组中,总体治愈率为29.6%,而接受溴隐亭治疗的患者治愈率为93.7%。准确的病史可突出最可能导致该病的病理生理机制。13.7%的患者疑似炎性乳腺癌需要进行组织学检查。(摘要截断于250字)

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