Division of Surgical Oncology, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Cancer J. 2010 Mar-Apr;16(2):111-7. doi: 10.1097/PPO.0b013e3181d7ea07.
Hepatic metastatic disease affects more than half of the patients with colorectal cancer and neuroendocrine cancer. Hepatic resection remains the gold standard for liver metastasis from colorectal and neuroendocrine primaries. Thermal ablative technologies, however, are increasingly being used either alone or in combination with resection to treat this group of patients. Radiofrequency ablation is the most common modality used in the United States, whereas microwave ablation has been more widely used in the East. In addition to being adjuncts to hepatic resection, ablation has gained an increased popularity in the management of patients who are not operative candidates or have unresectable colorectal or neuroendocrine hepatic metastasis. Although radiofrequency ablation seems to have a higher local recurrence than resection, ablation remains an important therapeutic option for many patients with hepatic metastasis.
肝转移瘤影响超过一半的结直肠癌和神经内分泌肿瘤患者。肝切除术仍然是结直肠和神经内分泌原发病灶肝转移的金标准。然而，热消融技术越来越多地被单独或联合切除术用于治疗这组患者。在美国，射频消融是最常用的方法，而微波消融在东方更为广泛应用。除了作为肝切除术的辅助手段外，消融术在治疗不能手术或不能切除的结直肠或神经内分泌肝转移的患者中也越来越受欢迎。虽然射频消融的局部复发率似乎高于切除术，但消融术仍然是许多肝转移患者的重要治疗选择。
