Gamblin T Clark, Christians Kathleen, Pappas Sam G
Medical College of Wisconsin, Division of Surgical Oncology, 9200 West Wisconsin Avenue, Milwaukee, WI 53226-3596, USA.
Surg Oncol Clin N Am. 2011 Apr;20(2):273-9, vii-viii. doi: 10.1016/j.soc.2010.11.002. Epub 2010 Dec 13.
Neuroendocrine cancer commonly metastasizes to the liver and often presents as unresectable disease. Liver resection or debulking most of the tumor provides a survival advantage for patients. Whether used alone or in combination with resection, radiofrequency ablation provides a unique tool to destroy metastases to the liver and spare hepatic parenchyma. Although randomized trials are lacking, retrospective series provide promising data to consider radiofrequency ablation in the management of hepatic neuroendocrine metastases.
神经内分泌癌通常会转移至肝脏,且常常表现为无法切除的疾病。肝切除或大部分肿瘤减瘤术可为患者带来生存优势。无论单独使用还是与切除术联合使用,射频消融都是一种独特的工具,可用于破坏肝转移灶并保留肝实质。尽管缺乏随机试验,但回顾性系列研究提供了有前景的数据,支持在肝神经内分泌转移瘤的治疗中考虑使用射频消融。