自体角膜缘结膜移植联合干细胞治疗翼状胬肉的疗效
Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment.
作者信息
Abdalla Walid M
机构信息
Department of Ophthalmology, Magrabi Eye and Ear Center, Muscat, Sultanate of Oman.
出版信息
Middle East Afr J Ophthalmol. 2009 Oct;16(4):260-2. doi: 10.4103/0974-9233.58417.
PURPOSE
To determine the efficacy of limbal-conjunctival autograft surgery with stem cells in the management of primary and recurrent pterygium and determine the best corrected visual acuity after surgery.
MATERIALS AND METHODS
Surgical excision of pterygium and limbal-conjunctival transplantation with stem cells was of 40 eyes (of 31 patients) with pterygium. Thirty one cases were primary and nine cases were recurrent pterygia. Graft margins were secured to the recipient site while stem cells aspect was sutured to the limbus.
RESULTS
After one year of follow-up, 37 of 40 (92.5%) eyes were free of recurrence. One of the three recurrent cases was aggressive (recurrence occurred two months after surgery) and the other two showed 2 mm corneal extension at 12 months follow-up. In 24 patients, out of 40 (60%), best corrected visual acuity improved more than two lines.
CONCLUSION
Limbal-conjunctival autograft surgery, including stem cells, appears to be an effective surgical technique in preventing pterygium recurrence and it can also help in improving the best corrected visual acuity.
目的
确定带干细胞的角膜缘-结膜自体移植手术治疗原发性和复发性翼状胬肉的疗效，并确定术后最佳矫正视力。
材料与方法
对40只眼（31例患者）的翼状胬肉进行手术切除并带干细胞的角膜缘-结膜移植。31例为原发性翼状胬肉，9例为复发性翼状胬肉。将移植片边缘固定于受体部位，同时将干细胞面缝合于角膜缘。
结果
随访一年后，40只眼中有37只（92.5%）无复发。3例复发病例中有1例为侵袭性（术后2个月复发），另外2例在随访12个月时角膜扩展2mm。40例患者中有24例（60%）最佳矫正视力提高超过两行。
结论
带干细胞的角膜缘-结膜自体移植手术似乎是预防翼状胬肉复发的一种有效手术技术，并且有助于提高最佳矫正视力。
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