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翼状胬肉手术的结膜自体移植:预防复发的效果如何?

Conjunctival autograft for pterygium surgery: how well does it prevent recurrence?

作者信息

Figueiredo R S, Cohen E J, Gomes J A, Rapuano C J, Laibson P R

机构信息

Cornea Service and Research Department, Thomas Jefferson University, Philadelphia, PA 19107-5598, USA.

出版信息

Ophthalmic Surg Lasers. 1997 Feb;28(2):99-104.

PMID:9054479
Abstract

BACKGROUND AND OBJECTIVE

The efficacy of the surgical management of pterygium with conjunctival autograft was evaluated.

PATIENTS AND METHODS

In a retrospective survey, the records of 94 consecutive patients who underwent surgery for pterygium between 1984 and 1993 were reviewed. Only the first pterygium procedure for each patient performed at Wills Eye Hospital was included. The statistical technique of survival curve analysis by the Kaplan-Meier product limit was used to analyze the results separately after the removal of primary and recurrent pterygia.

RESULTS

Thirty-one patients with primary pterygium underwent simple excision. Forty patients had conjunctival autografts. The recurrence rates estimated at 1 year were 40% and 16%, respectively (P= .031). In both groups, patients who were 50 years old or younger were more likely to have a recurrence (P = .029). All 23 patients with recurrent pterygium had conjunctival grafts, and the estimation of recurrence at 1 year was 25%. No serious complications occurred in any group. *

CONCLUSION

Conjunctival autograft decreases the recurrence rate for primary pterygium compared with simple excision.

摘要

背景与目的

评估自体结膜移植治疗翼状胬肉手术的疗效。

患者与方法

在一项回顾性调查中,对1984年至1993年间连续94例行翼状胬肉手术患者的记录进行了回顾。仅纳入每位患者在威尔斯眼科医院进行的首次翼状胬肉手术。采用Kaplan-Meier乘积限法的生存曲线分析统计技术,分别对原发性和复发性翼状胬肉切除后的结果进行分析。

结果

31例原发性翼状胬肉患者接受了单纯切除术。40例患者进行了自体结膜移植。1年时估计的复发率分别为40%和16%(P = 0.031)。在两组中,50岁及以下的患者更易复发(P = 0.029)。所有23例复发性翼状胬肉患者均接受了结膜移植,1年时复发率估计为25%。任何一组均未发生严重并发症。

结论

与单纯切除术相比,自体结膜移植可降低原发性翼状胬肉的复发率。

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