Nadkarni G D, Shimpi H H, Noronha O P
Radiation Medicine Centre, Tata Memorial Centre Annexe, Parel, Bombay.
Indian J Gastroenterol. 1991 Apr;10(2):51-3.
Comparable degree of liver cirrhosis, as judged by liver function tests and histopathology, was induced in rats by carbon tetrachloride. Comparative organ distribution of 99mTc-sulphur colloid and 99mTc-phytate was studied in the liver, spleen and lungs of these cirrhotic rats. Compared to controls, the biodistribution of 99mTc-sulphur colloid was found to be affected more than that of 99mTc-phytate in cirrhotic rats, especially at early time intervals.
通过肝功能测试和组织病理学判断，用四氯化碳在大鼠中诱导出了程度相当的肝硬化。在这些肝硬化大鼠的肝脏、脾脏和肺中研究了99mTc-硫胶体和99mTc-植酸盐的比较性器官分布。与对照组相比，发现肝硬化大鼠中99mTc-硫胶体的生物分布比99mTc-植酸盐受到的影响更大，尤其是在早期时间段。
