Huchon G, Akoun G
Sem Hop. 1977 Dec 16;53(43):2497-504.
Extrinsic allergic alveolitis of drug origin is now a better known branch of respiratory pathology. The symptoms and course of these cases resemble in many ways those of extrinsic allergic alveolitis in general with a few differences. The list of drugs responsible is longer every day, and it is important to be aware of it. The diagnosis of these diseases is not always easy, as there are certain similarities between them and other long diseases either iatrogenic or not, but not immuno-allergic. Our physiopathological knowledge is based on already known data concerning allergic alveolitis, but includes many theories which still have to be verified. It is important for the clinician to be aware of this new type of respiratory disease as the treatment includes withdrawal of the responsible drug as soon as possible, failing which irreversible pulmonary fibrosis develops.
药物源性外源性过敏性肺泡炎如今是呼吸病理学中一个广为人知的分支。这些病例的症状和病程在许多方面与一般的外源性过敏性肺泡炎相似，但也存在一些差异。导致该病的药物种类日益增多，了解这一点很重要。这些疾病的诊断并不总是容易的，因为它们与其他一些长期疾病（无论是医源性还是非医源性，但非免疫过敏性）存在某些相似之处。我们的病理生理学知识基于有关过敏性肺泡炎的已知数据，但也包含许多仍有待验证的理论。临床医生了解这种新型呼吸系统疾病很重要，因为治疗包括尽快停用致病药物，否则会发展为不可逆的肺纤维化。
