Radiation Safety Division, Soreq NRC, Yavne, Israel.
J Expo Sci Environ Epidemiol. 2011 Jul-Aug;21(4):365-71. doi: 10.1038/jes.2010.20. Epub 2010 Apr 21.
To advance our understanding of an association between exposure to power frequency magnetic fields (MFs) and the risk of childhood leukemia, we should conduct a study that is convincingly free of selection and response bias, with highly accurate exposure assessment and a large number of highly exposed individuals. Previous measurements revealed that MF in apartments located above internal transformer stations (ITSs) are higher than in other apartments in the same building. An international epidemiologic study of childhood leukemia, TransExpo, was designed to take advantage of this scenario. This article presents the results of an exposure assessment study performed in apartment buildings with ITS in Israel. Measurements were performed in 41 apartments within 10 buildings. Average MF at the height of 0.5 m was 0.40 μT in apartments above the ITS and 0.06-0.12 μT in all other apartments. These results confirm that classification of MF exposure based on apartment location is feasible with remarkable specificity (0.98 and 0.96 for cutoff points of 0.2 and 0.4 μT, respectively) and sensitivity (1.00 for both cutoff points). Because the location of an apartment relative to the ITS can be easily determined, an exposure assessment can reliably be performed without obtaining access to residences.
为了深入了解接触工频电磁场(MFs)与儿童白血病风险之间的关联,我们应该进行一项研究,该研究应完全避免选择和反应偏差,具有高度准确的暴露评估和大量的高暴露个体。先前的测量结果表明,位于内部变压器站(ITS)上方的公寓中的 MF 高于同一建筑物中其他公寓的 MF。一项针对儿童白血病的国际流行病学研究 TransExpo 就是基于这种情况而设计的。本文介绍了在以色列具有 ITS 的公寓楼中进行的暴露评估研究的结果。在 10 栋建筑物中的 41 套公寓中进行了测量。在 ITS 上方公寓中,0.5 m 高度处的平均 MF 为 0.40 μT,而所有其他公寓中的 MF 为 0.06-0.12 μT。这些结果证实,基于公寓位置对 MF 暴露进行分类是可行的,具有显著的特异性(分别为 0.2 和 0.4 μT 的截止点为 0.98 和 0.96)和敏感性(两个截止点均为 1.00)。由于公寓相对于 ITS 的位置可以轻松确定,因此可以在不进入住宅的情况下可靠地进行暴露评估。