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阴茎干广泛性鲍恩病分两次采用新鲜组织莫氏显微外科手术治疗。

Extensive Bowen's disease of the penile shaft treated with fresh tissue Mohs micrographic surgery in two separate operations.

作者信息

Moritz D L, Lynch W S

机构信息

Department of Dermatology, Case Western Reserve University, University Hospitals of Cleveland, Ohio 44106.

出版信息

J Dermatol Surg Oncol. 1991 Apr;17(4):374-8. doi: 10.1111/j.1524-4725.1991.tb01714.x.

DOI:10.1111/j.1524-4725.1991.tb01714.x
PMID:2040751
Abstract

Bowen's disease or squamous cell carcinoma in situ is uncommon on the penile shaft. While surgical excision is the treatment of choice, the Mohs micrographic surgical approach ensures microscopically controlled tumor-free margins with preservation of normal tissue. While small- or medium-sized penile excisions heal very well by second intention, large areas of involvement are often grafted to prevent debilitating contractures. We report a case of near circumferential penile Bowen's disease treated by two separate operations that healed by second intention with very good cosmetic and functional results.

摘要

鲍温病或原位鳞状细胞癌在阴茎干上并不常见。虽然手术切除是首选治疗方法,但莫氏显微外科手术方法可确保在显微镜控制下获得无肿瘤切缘,并保留正常组织。对于中小面积的阴茎切除,二期愈合效果很好,但大面积受累时通常需要植皮以防止严重挛缩。我们报告一例几乎累及整个阴茎周径的鲍温病病例,通过两次单独手术治疗,二期愈合,获得了非常好的美容和功能效果。

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Extensive Bowen's disease of the penile shaft treated with fresh tissue Mohs micrographic surgery in two separate operations.阴茎干广泛性鲍恩病分两次采用新鲜组织莫氏显微外科手术治疗。
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引用本文的文献

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Mohs Micrographic Surgery Versus Wide Local Excision in the Treatment of Anogenital Squamous Cell Carcinoma: A Systematic Review.莫氏显微外科手术与广泛局部切除治疗肛门生殖器鳞状细胞癌的系统评价
Int J Dermatol. 2025 Jun;64(6):1042-1048. doi: 10.1111/ijd.17689. Epub 2025 Feb 23.
2
Benefits and challenges of Mohs micrographic surgery for human papilloma virus-associated cutaneous malignancies: a systematic review.Mohs 显微外科治疗人乳头瘤病毒相关皮肤恶性肿瘤的益处和挑战:系统评价。
Arch Dermatol Res. 2024 Sep 14;316(9):617. doi: 10.1007/s00403-024-03364-8.