Schena Donatella, Papagrigoraki Anastasia, Frigo Anna, Girolomoni Giampiero
Department of Biomedical and Surgical Sciences, University of Verona, Italy.
Cutis. 2010 Mar;85(3):156-9.
Porokeratosis is a chronic skin disorder characterized by the presence of patches with elevated, thick, keratotic borders histologically featuring cornoid lamella. While porokeratosis usually is clinically defined by a slow onset, an eruptive variant has been reported. We report a 77-year-old woman affected by pancreatic carcinoma with-eruptive disseminated porokeratosis (EDP). We reviewed published cases of EDP developing suddenly or within a few months and found a total of 16 patients, 6 with internal malignancies of the liver or gastrointestinal tract. These findings suggest that patients with EDP should be investigated for the presence of internal malignancies.
