Torres Tiago, Velho Glória Cunha, Selores Manuela
Centro Hospitalar do Porto, Hospital de Santo António, Portugal.
An Bras Dermatol. 2010 Mar-Apr;85(2):229-31. doi: 10.1590/s0365-05962010000200016.
Porokeratosis refers to a group of hereditary or acquired disorders of epidermal keratinization and is characterized histologically by the presence of a cornoid lamella. The clinical variant referred to as disseminated superficial porokeratosis has been described in the literature in association with immunosuppressive conditions that include organ transplant, infections and immunosuppressive treatments. The association of disseminated superficial porokeratosis with solid organ malignancies has seldom been described, only 5 such cases having been published. The present report refers to a patient with lesions of disseminated superficial porokeratosis of sudden onset shortly before diagnosis of a cholangiocarcinoma.
汗孔角化症是指一组遗传性或获得性表皮角化障碍性疾病，其组织学特征为存在鸡眼样板层。文献中已描述了称为播散性浅表性汗孔角化症的临床变体与包括器官移植、感染和免疫抑制治疗在内的免疫抑制状况有关。播散性浅表性汗孔角化症与实体器官恶性肿瘤的关联很少被描述，仅发表了5例此类病例。本报告涉及一名在胆管癌诊断前不久突然出现播散性浅表性汗孔角化症病变的患者。
