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实验性戊型肝炎病毒脑炎的电子显微镜研究

An electron microscopic study of experimentally-induced HEV encephalitis.

作者信息

Meyvisch C, Hoorens J

出版信息

Vet Pathol. 1978 Jan;15(1):102-13. doi: 10.1177/030098587801500112.

DOI:10.1177/030098587801500112
PMID:204096
Abstract

A gnobiotic piglet, was inoculated intracerebrally with hemagglutinating encephalomyelitis virus (strain VW572). Mononuclear cells formed vascular cuffs and were disseminated in the brain parenchyma. A few neurons were surrounded by the same kind of cells. Virus particles morphologically similar to coronavirus particles were found in the cytoplasm of both chromatolytic light neurons and hyperchromic dark neurons. The particles were in vesicles of distended endoplasmic reticulum and in the hypertrophied Golgi apparatus.

摘要

将一头无菌仔猪脑内接种血凝性脑脊髓炎病毒(VW572株)。单核细胞形成血管套并散布于脑实质中。少数神经元被同种细胞包围。在嗜色性淡神经元和嗜色性深神经元的细胞质中均发现形态上与冠状病毒颗粒相似的病毒颗粒。这些颗粒存在于扩张的内质网囊泡和肥大的高尔基体中。

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