Arrhythmia Section, Division of Cardiology, Zentralklinik Bad Berka, Robert Koch Allee, 9, Bad Berka 99437, Germany.
Europace. 2010 Jul;12(7):933-40. doi: 10.1093/europace/euq110. Epub 2010 Apr 21.
The aim of the study was to determine the level of pulmonary vein (PV) isolation achieved with the use of a novel radiofrequency circular multielectrode ablation catheter [pulmonary vein ablation catheter (PVAC)] in patients with paroxysmal atrial fibrillation. Although some efficacy data have been presented, the level of PV isolation, which is crucial both for efficacy and safety of the ablation, has not been defined with this new ablation catheter.
Detailed sinus rhythm voltage maps using an electroanatomic mapping system and projected on 3D computed tomography-derived reconstructions of the left atrium (LA) were obtained before and after PV isolation with the PVAC. Left atrium-PV entry and exit block was assessed for each vein. The population consisted of 12 patients, mean age 57+/-6 years, seven male. After ablation, an extensive zone of potential reduction that included the ostium of each PV was observed in all patients. Bipolar voltages were significantly reduced in all PVs and in the LA close to the vein ostia, the mean voltage reduction was >80%.
Using the PVAC, (i) PVs are isolated at the level of the PV ostium and, importantly, outside the tubular portion and (ii) significant voltage reduction is also recorded at various extent proximal to the PV ostium at the level of the antral region.
本研究旨在确定使用新型射频环形多电极消融导管(肺静脉消融导管,PVAC)在阵发性心房颤动患者中实现肺静脉(PV)隔离的程度。尽管已经提出了一些疗效数据,但对于消融的疗效和安全性至关重要的 PV 隔离程度尚未用这种新的消融导管来定义。
使用电生理标测系统获得窦性心律电压图,并在使用 PVAC 进行 PV 隔离前后投射到左心房(LA)的 3D 计算机断层扫描重建上。评估每条静脉的左心房-PV 入口和出口阻滞。该人群包括 12 名患者,平均年龄 57±6 岁,男性 7 名。消融后,在所有患者中均观察到包括每个 PV 口在内的广泛的潜在减少区域。所有 PV 中的双极电压显著降低,靠近静脉口的左心房也显著降低,平均电压降低>80%。
使用 PVAC,(i)PV 在 PV 口水平处被隔离,重要的是,在管状部分之外;(ii)在窦房结区域水平的 PV 口近端的不同程度上也记录到显著的电压降低。