Department of Health Sciences Research, Mayo Clinic School of Medicine, Rochester, MN, USA.
J Arthroplasty. 2011 Apr;26(3):366-374.e1. doi: 10.1016/j.arth.2010.02.006. Epub 2010 Apr 21.
We assessed whether higher body mass index (BMI) is associated with higher risk of moderate-severe knee pain 2 and 5 years after primary or revision total knee arthroplasty (TKA).We adjusted for sex, age, comorbidity, operative diagnosis, and implant fixation in multivariable logistic regression. Body mass index (reference, b 25 kg/m2) was not associated with moderate severe knee pain at 2 years post primary TKA (odds ratio [95% confidence interval], 25-29.9, 1.02[0.75-1.39], P = .90; 30-34.9, 0.93 [0.65-1.34], P = .71; 35-39.9, 1.16 [0.77-1.74], P = .47; ≥ 40,1.09 [0.69-1.73], [all P values ≥ .47]). Similarly, BMI was not associated with moderate-severe pain at 5-year primary TKA and at 2-year and 5-year revision TKA follow-up. Lack of association of higher BMI with poor pain outcomes post-TKA implies that TKA should not be denied to obese patients for fear of suboptimal outcomes.
我们评估了较高的体重指数(BMI)是否与初次或翻修全膝关节置换术后 2 年和 5 年时出现中度至重度膝关节疼痛的风险较高有关。我们在多变量逻辑回归中调整了性别、年龄、合并症、手术诊断和植入物固定。体重指数(参考,b 25kg/m2)与初次 TKA 后 2 年的中度至重度膝关节疼痛无关(比值比[95%置信区间],25-29.9,1.02[0.75-1.39],P=0.90;30-34.9,0.93 [0.65-1.34],P=0.71;35-39.9,1.16 [0.77-1.74],P=0.47;≥40,1.09 [0.69-1.73],所有 P 值均≥0.47)。同样,BMI 与初次 TKA 后 5 年、翻修 TKA 后 2 年和 5 年的中度至重度疼痛无关。较高 BMI 与 TKA 后疼痛结局不佳无关表明,不应因担心手术结果不理想而拒绝为肥胖患者进行 TKA。