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[角膜滴状变性与富克斯内皮-上皮营养不良。73例患者的临床组织学研究]

[Cornea guttata and Fuchs' endothelial-epithelial dystrophy. Clinico-histologic study of 73 patients].

作者信息

Lisch W, Buob M, Steuhl K P

机构信息

Abteilung I, Univ. Augenklinik Tübingen.

出版信息

Klin Monbl Augenheilkd. 1991 Feb;198(2):83-6. doi: 10.1055/s-2008-1045935.

DOI:10.1055/s-2008-1045935
PMID:2041372
Abstract

In a retrospective, clinico-histological study, 84 corneas from 73 patients with diagnosed Fuchs' dystrophy (FD) were examined after penetrating keratoplasty. Seven types of posterior corneal degeneration were found: six with diversely arranged and pronounced guttae and a thickened Descemet's membrane, and a seventh with no guttae in either eye. This last variant appeared histologically in only two patients. Whether it represents a different syndrome can only be speculated. Our study showed, however, that the frequency of cornea guttata (CG) in FD is statistically significant in all the histological variants.

摘要

在一项回顾性临床组织学研究中,对73例诊断为富克斯角膜内皮营养不良(FD)患者行穿透性角膜移植术后的84只角膜进行了检查。发现了七种类型的角膜后弹力层变性:六种表现为滴状赘疣排列多样且明显,后弹力层增厚,第七种两眼均无滴状赘疣。最后这种变异型仅在两名患者中出现组织学表现。它是否代表一种不同的综合征只能进行推测。然而,我们的研究表明,在所有组织学变异型中,FD患者角膜滴状变性(CG)的发生率具有统计学意义。

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