Lisch W, Buob M, Steuhl K P
Abteilung I, Univ. Augenklinik Tübingen.
Klin Monbl Augenheilkd. 1991 Feb;198(2):83-6. doi: 10.1055/s-2008-1045935.
In a retrospective, clinico-histological study, 84 corneas from 73 patients with diagnosed Fuchs' dystrophy (FD) were examined after penetrating keratoplasty. Seven types of posterior corneal degeneration were found: six with diversely arranged and pronounced guttae and a thickened Descemet's membrane, and a seventh with no guttae in either eye. This last variant appeared histologically in only two patients. Whether it represents a different syndrome can only be speculated. Our study showed, however, that the frequency of cornea guttata (CG) in FD is statistically significant in all the histological variants.
在一项回顾性临床组织学研究中,对73例诊断为富克斯角膜内皮营养不良(FD)患者行穿透性角膜移植术后的84只角膜进行了检查。发现了七种类型的角膜后弹力层变性:六种表现为滴状赘疣排列多样且明显,后弹力层增厚,第七种两眼均无滴状赘疣。最后这种变异型仅在两名患者中出现组织学表现。它是否代表一种不同的综合征只能进行推测。然而,我们的研究表明,在所有组织学变异型中,FD患者角膜滴状变性(CG)的发生率具有统计学意义。