Efthimiou I, Skrepetis K, Bournia E
Department of Urology, General Hospital of Chios, Chios, Greece.
J BUON. 2010 Jan-Mar;15(1):19-24.
Adoption of screening programmes for early diagnosis of prostate cancer has led to an increased number of sonographically guided prostate biopsies. Core needle biopsies are now among the most common specimens received from pathology laboratories. As a result, urologists and pathologists may encounter small volume prostate tumors with obvious clinical and diagnostic implications. These cases may be extremely challenging for two reasons. The diagnosis of small cancer foci is a challenge for pathologists as it carries the risk of false positive or negative diagnosis. Additionally, it represents a difficult clinical dilemma for urologists whether they should proceed or withhold treatment for local disease. This report highlights current concepts regarding pathologic diagnosis and clinical management of these cases.
采用前列腺癌早期诊断筛查方案导致超声引导下前列腺活检数量增加。现在，芯针活检是病理实验室接收的最常见标本之一。因此，泌尿外科医生和病理科医生可能会遇到体积小但具有明显临床和诊断意义的前列腺肿瘤。这些病例可能极具挑战性，原因有两个。对病理科医生来说，诊断小癌灶是一项挑战，因为存在假阳性或假阴性诊断的风险。此外，对于泌尿外科医生而言，这也构成了一个艰难的临床困境，即他们是否应该对局部疾病进行治疗。本报告重点介绍了有关这些病例的病理诊断和临床管理的当前概念。
