Department of Nuclear Medicine, Derriford Hospital, Plymouth, UK.
Clin Imaging. 2010 May-Jun;34(3):179-84. doi: 10.1016/j.clinimag.2009.05.002.
The use of plasma D-dimer assay has been advocated for the exclusion of pulmonary embolism. We retrospectively looked at 840 patients in whom both ventilation-perfusion scan and D-dimer assay were performed within 48 h. The negative predictive value of a negative D-dimer assay was 96% for emergency admissions and 98% for inpatients. We present the cases of two patients with negative D-dimer assay results who had a high-probability lung scan, and we have found a further three patients with negative D-dimer assay results who had an intermediate-probability lung scan.
已有研究推荐使用血浆 D-二聚体检测排除肺栓塞。我们回顾性分析了 840 例在 48 小时内行通气灌注扫描和 D-二聚体检测的患者。急诊入院患者 D-二聚体检测阴性的阴性预测值为 96%，住院患者为 98%。我们报告了两例 D-二聚体检测阴性但肺扫描高度可能的患者，并发现了另外三例 D-二聚体检测阴性但肺扫描中度可能的患者。
