De Quadros C A, Andrus J K, Olivé J M, Da Silveira C M, Eikhof R M, Carrasco P, Fitzsimmons J W, Pinheiro F P
Pan American Health Organization, Expanded Program on Immunization, Washington, DC 20037.
Pediatr Infect Dis J. 1991 Mar;10(3):222-9. doi: 10.1097/00006454-199103000-00011.
In the span of 5 years since the eradication initiative was launched and only 3 years since external funds were made available, PAHO has been able to develop and implement a comprehensive program strategy for polio eradication that includes the following components: achievement and maintenance of high immunization levels (which include the supplemental strategies of national immunization days and mop-up operations); effective surveillance to detect all new cases; and a rapid response to the occurrence of new cases. Despite yearly increases in the number of cases of acute flaccid paralysis reported to the surveillance system, a decline in reported confirmed cases of polio has occurred since 1986 to record low levels in 1989. Cases in 1989 were reported from only 0.7% of the counties in the Americas. The occurrence of 24 wild-type virus isolates in 1989 were limited to only three geographic areas: northwestern Mexico; the northern Andean Region; and northeastern Brazil. At this writing the clock is ticking with only 3 months left to achieve the goal of interrupting transmission by the end of 1990. If the current level of effort is sustained and special efforts are directed at the remaining foci of infection, the eradication of the transmission of wild-type poliovirus from the Americas can be achieved. Continued external financial support will be critical if the effort is to succeed. The prospect of poliomyelitis eradication in the Americas led the 41st World Health Assembly of WHO to adopt a resolution in May, 1988, to eradicate the indigenous transmission of wild-type poliovirus from the world by the year 2000.(ABSTRACT TRUNCATED AT 250 WORDS)
自根除计划启动后的5年里,且仅在有外部资金可用的3年后,泛美卫生组织已能够制定并实施一项全面的根除脊髓灰质炎计划战略,该战略包括以下几个部分:实现并维持高免疫水平(其中包括全国免疫日和扫荡行动等补充策略);进行有效监测以发现所有新病例;以及对新病例的出现做出快速反应。尽管向监测系统报告的急性弛缓性麻痹病例数量逐年增加,但自1986年以来,报告的脊髓灰质炎确诊病例数已有所下降,并在1989年降至历史最低水平。1989年的病例仅来自美洲0.7%的县。1989年出现的24株野生型病毒分离株仅局限于三个地理区域:墨西哥西北部;安第斯北部地区;以及巴西东北部。撰写本文时,距离1990年底实现阻断传播的目标仅剩3个月时间。如果维持当前的努力水平,并针对其余感染源做出特别努力,就能够在美洲根除野生型脊髓灰质炎病毒的传播。如果要取得成功,持续的外部财政支持将至关重要。美洲根除脊髓灰质炎的前景促使世界卫生组织第41届世界卫生大会于1988年5月通过一项决议,到2000年在全球根除野生型脊髓灰质炎病毒的本土传播。(摘要截选至250词)