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[美洲大陆根除脊髓灰质炎]

[Eradication of poliomyelitis from the American continent].

作者信息

Olivé J M, de Quadros C A

机构信息

EPI/PAHO (WHO), Programme élargi de vaccination, Organisation panaméricaine de la santé, Washington, DC 20037-2895.

出版信息

Sante. 1994 May-Jun;4(3):151-5.

PMID:7522869
Abstract

A strategy to eradicate poliomyelitis from America was developed in 1985 by the PAHO. The last case of poliomyelitis due to wild virus was detected in August 1991 in the Andean region of Peru. The main strategies used to eradicate polio are: 1) attainment of high immunization levels, 2) biannual National Vaccination Campaigns with OPV in all poliomyelitis infected countries, 3) organization in all America countries of effective surveillance of AFP, 4) setting up of a laboratory network for the isolation of the wild poliovirus from cases and contacts' stools samples and 5) the organization of a rapid response, to the occurrence of any new case with door to door vaccination (Mop-up). These strategies have been recommended by the WHO for Global Eradication of Poliomyelitis by the Year 2000. The next step in the Americas is to confirm the eradication of poliomyelitis. An ICPEC has been organized and the condition required to certify the eradication is the absence of cases of virologically confirmed indigenous poliomyelitis by a period of at least three years in the context of continued adequate surveillance. Four elements will be taken into consideration when confirming the eradication of poliomyelitis: 1) the surveillance of AFP, 2) the surveillance of wild poliovirus, 3) active searches for AFP cases in areas of risk, such as those areas with poor surveillance, or where there have been compatible cases, 4) documentation of mop-up operations in areas of risk.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

泛美卫生组织于1985年制定了一项在美洲根除脊髓灰质炎的战略。1991年8月在秘鲁安第斯地区发现了最后一例由野生病毒引起的脊髓灰质炎病例。用于根除脊髓灰质炎的主要战略有:1)实现高免疫水平;2)在所有脊髓灰质炎感染国家每两年开展一次口服脊髓灰质炎疫苗国家免疫运动;3)在美洲所有国家组织对急性弛缓性麻痹(AFP)进行有效监测;4)建立实验室网络,从病例及接触者的粪便样本中分离野生脊髓灰质炎病毒;5)针对任何新病例的出现组织快速反应,进行挨家挨户接种疫苗( mop-up)。这些战略已被世界卫生组织推荐用于到2000年在全球根除脊髓灰质炎。美洲的下一步是确认根除脊髓灰质炎。已经组织了一个根除脊髓灰质炎国际认证委员会(ICPEC),认证根除所需的条件是在持续充分监测的情况下,至少三年没有病毒学确诊的本土脊髓灰质炎病例。在确认根除脊髓灰质炎时将考虑四个要素:1)对AFP的监测;2)对野生脊髓灰质炎病毒的监测;3)在风险地区,如监测不力地区或有类似病例的地区,积极搜索AFP病例;4)记录风险地区的 mop-up行动。(摘要截短为250字)

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