Department of Anesthesiology, Hospital del Mar, Institut Municipal d'Investigació Mèdica, Barcelona, Spain.
Anesthesiology. 2010 May;112(5):1164-74. doi: 10.1097/ALN.0b013e3181d3e017.
Health-related quality of life is usually reported for specific rather than heterogeneous populations such as those treated in routine anesthesia practice. The 8-item short-form generic health-related quality-of-life questionnaire (SF-8) is a candidate instrument for this setting. The authors evaluated the feasibility, reliability, validity, and responsiveness to change of the Spanish version of SF-8 in a population-based surgical cohort.
Recruiting patients from a large population-based study of risk factors for pulmonary complications, before surgery, the authors administered the 1-week recall SF-8 to 2,991 patients undergoing nonobstetric elective or emergency surgery in 59 hospitals, each of which collected data on seven randomly assigned days in 2006. The SF-8 was administered again 3 months later. Reliability was evaluated using the Cronbach alpha coefficient and validity by comparing physical and mental component summary SF-8 scores with clinical variables. Responsiveness after surgery was evaluated using the standardized response mean.
Cronbach alpha for the overall test was 0.92. Physical and mental component summary scores and all individual scores were lower (worse quality of life) in women (P < 0. 01) and decreased with age (P < 0.01). Preoperative scores were lower for those in worse clinical condition (higher body mass index, American Society of Anesthesiologists physical status class, or surgical risk scores), with preoperative respiratory symptoms, and in emergency situations (P < 0.01). The standardized response mean ranged from 0.1 to 0.5.
The SF-8 is a feasible, reliable, valid, and responsive instrument for assessing health-related quality of life in a broad-spectrum surgical population.
健康相关生活质量通常是针对特定人群而非异质人群（如在常规麻醉实践中接受治疗的人群）报告的。8 项简短形式通用健康相关生活质量问卷（SF-8）是这种情况下的候选工具。作者评估了基于人群的手术队列中 SF-8 西班牙版本的可行性、可靠性、有效性和对变化的反应性。
作者从一项关于肺部并发症危险因素的大型基于人群的研究中招募患者，在手术前，对 2991 名接受非产科择期或急诊手术的患者使用 1 周回顾 SF-8 进行调查，其中 59 家医院每家在 2006 年的 7 天随机日收集数据。SF-8 再次在 3 个月后进行评估。可靠性通过 Cronbach alpha 系数进行评估，有效性通过比较身体和精神成分综合 SF-8 评分与临床变量进行评估。手术后的反应性通过标准化反应均值进行评估。
总体测试的 Cronbach alpha 为 0.92。身体和精神成分综合评分以及所有单项评分在女性中较低（生活质量较差）（P < 0.01），并随年龄增长而降低（P < 0.01）。术前评分在临床状况较差的患者（体重指数较高、美国麻醉医师协会身体状况分级或手术风险评分较高）、术前有呼吸系统症状和急诊情况下较低（P < 0.01）。标准化反应均值范围从 0.1 到 0.5。
SF-8 是一种可行、可靠、有效的工具，可用于评估广谱手术人群的健康相关生活质量。
