Bandyopadhyay Debabrata, Ghosh Sudip Kumar
Department of Dermatology, STD, and Leprosy, R. G. Kar Medical College, Kolkata 700 004, India.
Indian J Dermatol. 2010;55(1):64-7. doi: 10.4103/0019-5154.60356.
Chikungunya fever (CF) is an arboviral acute febrile illness transmitted by the bite of infected Aedes mosquitoes. After a quiescence of more than three decades, CF has recently re-emerged as a major public health problem of global scale. CF is characterized by an acute onset of high fever associated with a severe disabling arthritis often accompanied by prominent mucocutaneous manifestations. The disease is usually self-limiting, but the joint symptoms and some of the cutaneous features may persist after the defervescence. A wide range of mucocutaneous changes has been described to occur in association with CF during the current epidemic. Besides a morbilliform erythema, hyperpigmentation, xerosis, excoriated papules, aphthous-like ulcers, vesiculobullous and lichenoid eruptions, and exacerbation of pre-existing or quiescent dermatoses had been observed frequently. These unusual features may help in the clinical differential diagnosis of acute viral exanthems mimicking CF.
基孔肯雅热（CF）是一种由受感染的伊蚊叮咬传播的虫媒病毒急性发热性疾病。在沉寂了三十多年后，基孔肯雅热最近再次出现，成为一个全球范围内的重大公共卫生问题。基孔肯雅热的特点是急性高热发作，伴有严重的致残性关节炎，常伴有明显的皮肤黏膜表现。该病通常为自限性，但退热后关节症状和一些皮肤特征可能持续存在。在当前疫情期间，已描述了与基孔肯雅热相关的多种皮肤黏膜变化。除了麻疹样红斑外，还经常观察到色素沉着、皮肤干燥、丘疹抓破、口疮样溃疡、水疱大疱性和苔藓样皮疹，以及既往或静止性皮炎的加重。这些不寻常的特征可能有助于对模仿基孔肯雅热的急性病毒疹进行临床鉴别诊断。
