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[一名服用阿拉普利引发舌血管性水肿患者成功拔管]

[Successful extubation in a patient with alacepril-induced tongue angioedema].

作者信息

Katoh Hiromi, Itagaki Taiga, Suzuki Katsumi, Obata Yukako, Adachi Yushi, Doi Matsuyuki, Sato Shigehito

机构信息

Intensive Care Unit of University Hospital, Hamamatsu University School of Medicine, Hamamatsu 431-3192.

出版信息

Masui. 2010 Apr;59(4):519-22.

Abstract

We describe a case of marked swelling of the tongue in a patient after a long prone position neurosurgery, who was treated for hypertension with alacepril. The tongue was not congestive and history of taking an angiotensin-converting enzyme inhibitor suggested an alacepril-induced angioedema. The day after surgery, the patient's tongue was still swollen; however, fibrescopic observation of the larynx and pharynx through the nasal cavity revealed that the edema was limited to anterior tongue, and the oral cavity and oropharynx were not involved. Although, tongue angioedema was observed, we introduced a 3-mm tube exchanger to the patient's trachea and removed the endotracheal tube. The ventilation and oxygenation were maintained, and 30 min later, the exchanger was detached. On the second postoperative day, the angioedema disappeared completely and the patient was transferred to a ward without any complication.

摘要

我们描述了一例在长时间俯卧位神经外科手术后出现舌头明显肿胀的患者,该患者正在服用阿拉普利治疗高血压。舌头无充血,服用血管紧张素转换酶抑制剂的病史提示为阿拉普利诱发的血管性水肿。术后第二天,患者的舌头仍肿胀;然而,通过鼻腔对喉和咽进行纤维镜观察发现,水肿仅限于舌前部,口腔和口咽未受累。尽管观察到舌头血管性水肿,我们仍为患者的气管插入了一根3毫米的换管器并拔除了气管内插管。维持了通气和氧合,30分钟后,拔除了换管器。术后第二天,血管性水肿完全消失,患者被转至病房,无任何并发症。

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