O'Mara N B, O'Mara E M
Department of Pharmacy, Methodist Hospital, Indianapolis, IN 46206, USA.
Pharmacotherapy. 1996 Jul-Aug;16(4):675-9.
The angiotensin-converting enzyme inhibitors have gained widespread application in the management of hypertension and congestive heart failure, and after myocardial infarction. They are generally considered safe drugs, but there are a number of reports of angioedema associated with their use. In general, angioedema occurs within hours to days after initiation of therapy, and only a limited number of reports document a delayed onset. Our patient experienced angioedema after 14 months of therapy with benazepril.
血管紧张素转换酶抑制剂已广泛应用于高血压、充血性心力衰竭的治疗以及心肌梗死后的治疗。它们通常被认为是安全的药物，但有许多关于其使用相关血管性水肿的报道。一般来说，血管性水肿在治疗开始后的数小时至数天内发生，仅有少数报道记录有延迟发作的情况。我们的患者在使用贝那普利治疗14个月后出现了血管性水肿。
