Johnson Laura, Gunasekera Ayanthi, Douek Michael
Department of Research Oncology, King's College London, London SE1 9RT, United Kingdom.
Discov Med. 2010 Apr;9(47):374-9.
Modern cancer therapy is more individualized to specific cancer subtypes, in an attempt to treat those patients who are likely to obtain greater benefit and avoid treatment induced side effects in those who will not. Nanotechnology heralds an era whereby cancer could be diagnosed by a single agent, treated simultaneously while the diagnosis is being made, and its response to treatment monitored. Whilst nanotechnology is still mostly in the research stage, several applications are ready for translation from the bench to the bedside, in particular in the field of breast cancer. This is exciting new area of research where science fiction may become a reality.
现代癌症治疗更加针对特定的癌症亚型进行个体化,旨在治疗那些可能获得更大益处的患者,并避免对无获益患者造成治疗引起的副作用。纳米技术开创了一个时代,即癌症可以通过单一制剂进行诊断,在诊断的同时进行同步治疗,并监测其对治疗的反应。虽然纳米技术大多仍处于研究阶段,但有几种应用已准备好从实验室转化到临床应用,尤其是在乳腺癌领域。这是一个令人兴奋的新研究领域,科幻小说可能会成为现实。