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[药物成瘾母亲的新生儿:母亲、围产期、新生儿方面及新生儿戒断综合征]

[Newborn infant of drug-addicted mother: maternal, perinatal, neonatal aspects, and neonatal abstinence syndrome].

作者信息

Arcas Cruz R, Figueras Aloy J, Vilanova Juanola J M, Comas Mastmitja L, Jiménez González R, Cruz Hernández M

机构信息

Subdivisión de Pediatría, Hospital Clínico y Facultad de Medicina, Universidad de Barcelona.

出版信息

An Esp Pediatr. 1991 Feb;34(2):123-7.

PMID:2042804
Abstract

Maternal drug addiction has increased in an alarming way over the last ten years. Therefore, the withdrawal syndrome in the newborn has also increased. 53% of the newborns (of chemical dependent mother) studied from 1985 to 1989 in HCP have presented this syndrome. We have analysed: perinatal, neonatal and maternal factors, and their clinical features and treatment: There is a great incidence of perinatal asphyxia, acidosis, premature rupture of the fetal membranes, etc. The newborns are usually premature or of low birth weight for their gestational age. They present diverse pathology: syphilis, HBsAg +, HIV +, gonorrhea, congenital malformations, etc. The mothers are often prostitutes, belong to a low socioeconomic status, have had previous abortions and have had no control of the actual pregnancy, etc. The syndrome of abstinence presents with: jitteriness, sweating, high-pitched or continuous crying, vomits, diarrhea, and even seizures. The neurological and digestive manifestations are the most difficult to treat. The treatment consists of general measures (little stimulation dim light, etc.), phenobarbital, and chlorpromazine.

摘要

在过去十年中,母亲药物成瘾现象以惊人的速度增长。因此,新生儿戒断综合征的发生率也有所上升。1985年至1989年在哈莱姆医院中心(HCP)研究的(母亲有药物依赖的)新生儿中,53%出现了这种综合征。我们分析了围产期、新生儿期和母亲因素,以及它们的临床特征和治疗方法:围产期窒息、酸中毒、胎膜早破等情况发生率很高。这些新生儿通常早产或相对于其孕周出生体重偏低。他们存在多种病症:梅毒、乙肝表面抗原阳性、艾滋病毒阳性、淋病、先天性畸形等。母亲往往是妓女,社会经济地位低下,有过堕胎史,且未对此次怀孕进行管控等。戒断综合征的表现有:易激惹、出汗、高音调或持续性哭闹、呕吐、腹泻,甚至惊厥。神经和消化系统表现最难治疗。治疗措施包括一般措施(尽量减少刺激、光线昏暗等)、苯巴比妥和氯丙嗪。

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