Cong A, Cong W, Shen H, Wang G, Lu Y, Chatziioannou A
VT-WFU School of Biomedical Eng & Sci, Virginia Tech.
Proc IEEE Int Symp Biomed Imaging. 2009 Jun 28:446-449. doi: 10.1109/ISBI.2009.5193080.
Recently, we generalized the Delta-Eddington phase function and applied it to the radiative transfer equation for modeling the photon propagation in biological tissue. The resultant phase approximation model was shown to be highly accurate with a wide range of optical properties, including the strongly absorbing and weakly scattering media. In this paper, we propose phase-approximation-based method for estimating the optical parameters. Specifically, we design an iterative algorithm to take advantage of both the global search ability of the differential evolution algorithm and the efficiency of the conjugate gradient method. Then, we demonstrate the feasibility and merits of the proposed method in both numerical simulation and phantom experiments.
最近，我们对Delta - 爱丁顿相函数进行了推广，并将其应用于辐射传输方程，以模拟光子在生物组织中的传播。结果表明，所得的相位近似模型在广泛的光学特性范围内都具有很高的准确性，包括强吸收和弱散射介质。在本文中，我们提出了一种基于相位近似的光学参数估计方法。具体而言，我们设计了一种迭代算法，以利用差分进化算法的全局搜索能力和共轭梯度法的效率。然后，我们在数值模拟和体模实验中证明了该方法的可行性和优点。
