Obstetrics/Gynecology Department, Hospital Geral, Fundação Universidade de Caxias do Sul, RS, Brazil.
Braz J Infect Dis. 2010 Jan-Feb;14(1):24-9. doi: 10.1590/s1413-86702010000100006.
to determine the seroprevalence rate of toxoplasmosis, HIV, syphilis and rubella in a population of puerperal women.
a prospective, cross-sectional study was performed from February 2007 to April 2008 at Hospital Geral, Universidade de Caxias do Sul in a population of 1,510 puerperal women. Women that gave birth to live born or stillborn infants were included in the study; maternal and perinatal variables were analyzed. Descriptive statistics and Pearson's chi-square with occasional Fisher's correction were used for comparisons. Alpha was set in 5%.
a total of 148 cases of congenital infection (9.8%) were identified: 66 cases of syphilis (4.4%), 40 cases of HIV (2.7%), 27 cases of toxoplasmosis (1.8%) and 15 cases of rubella (1.0%). In ten cases there was co-infection (four cases of HIV and syphilis, two cases of HIV and rubella, one case of HIV and toxoplasmosis, two cases of rubella and syphilis, and one case of toxoplasmosis and rubella). In a comparison between puerperal women with and without infection there was no statistical significance in relation to incidence of abortions, small for gestational age, prematurity, live births and stillbirths, and prenatal care. Need of neonatal intensive care unit (NICU), maternal schooling, maternal age higher than 35 years and drug use (alcohol, cocaine and crack) had statistical significance.
the prevalence rate of infections was 9.8%. Need of NICU, maternal schooling lower than eight years, maternal age higher than 35 years and drug use were significantly associated with occurrence of congenital infection.
确定产后妇女群体中弓形虫病、HIV、梅毒和风疹的血清流行率。
这是一项于 2007 年 2 月至 2008 年 4 月在 Caxias do Sul 大学综合医院进行的前瞻性、横断面研究，研究对象为 1510 名产后妇女。本研究纳入了分娩出活产或死产婴儿的产妇；分析了产妇和围产期变量。采用描述性统计和 Pearson 卡方检验（偶尔用 Fisher 校正）进行比较。α 值设定为 5%。
共发现 148 例先天性感染病例（9.8%）：66 例梅毒（4.4%），40 例 HIV（2.7%），27 例弓形虫病（1.8%）和 15 例风疹（1.0%）。在 10 例病例中存在合并感染（4 例 HIV 和梅毒、2 例 HIV 和风疹、1 例 HIV 和弓形虫病、2 例风疹和梅毒、1 例弓形虫病和风疹）。在感染与未感染的产后妇女之间进行比较，在流产、胎儿小于胎龄、早产、活产和死产以及产前保健方面，差异无统计学意义。新生儿重症监护病房（NICU）的需求、母亲受教育程度较低（低于 8 年）、母亲年龄大于 35 岁和药物使用（酒精、可卡因和冰毒）具有统计学意义。
感染率为 9.8%。需要进入 NICU、母亲受教育程度低于 8 年、母亲年龄大于 35 岁和药物使用与先天性感染的发生显著相关。
