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巴西东北部地区人类免疫缺陷病毒感染者合并感染的流行情况。

Prevalence of coinfections in women living with human immunodeficiency virus in Northeast Brazil.

机构信息

Universidade Federal de Sergipe, Programa de Pós-Graduação em Enfermagem, São Cristóvão, SE, Brasil.

Universidade Federal de Alagoas, Núcleo de Epidemiologia e Saúde Pública, Arapiraca, AL, Brasil.

出版信息

Rev Soc Bras Med Trop. 2019 Dec 20;53:e20190282. doi: 10.1590/0037-8682-0282-2019. eCollection 2019.

DOI:10.1590/0037-8682-0282-2019
PMID:31859952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7083350/
Abstract

INTRODUCTION

Despite the success of antiretrovirals, human immunodeficiency virus (HIV) coinfections continue to cause mortality. We investigated the prevalence of coinfections in women with HIV/acquired immunodeficiency syndrome in Sergipe, Brazil.

METHODS

We conducted a cross-sectional study. The coinfections investigated were syphilis, hepatitis B and C, toxoplasmosis, rubella, tuberculosis, and cytomegalovirus.

RESULTS

Among the 435 women, 85 (19.5%) had coinfections. The most prevalent was HIV/syphilis, followed by tuberculosis, toxoplasmosis, hepatitis C, hepatitis B, and rubella. Additionally, 300 (96.2%) were seropositive for cytomegalovirus immunoglobulin G.

CONCLUSIONS

Despite significant progress in the treatment for people with HIV, coinfections continued to affect this population.

摘要

简介

尽管抗逆转录病毒药物取得了成功,但人类免疫缺陷病毒(HIV)合并感染仍会导致死亡。我们调查了巴西塞尔希培州 HIV/获得性免疫缺陷综合征女性患者的合并感染患病率。

方法

我们进行了一项横断面研究。调查的合并感染包括梅毒、乙型肝炎和丙型肝炎、弓形虫病、风疹、结核病和巨细胞病毒。

结果

在 435 名女性中,85 人(19.5%)存在合并感染。最常见的是 HIV/梅毒,其次是结核病、弓形虫病、丙型肝炎、乙型肝炎和风疹。此外,300 人(96.2%)的巨细胞病毒免疫球蛋白 G 呈阳性。

结论

尽管 HIV 患者的治疗取得了重大进展,但合并感染仍在影响这一人群。