Inagaki Ana Dorcas de Melo, Oliveira Lívia Albuquerque Resende de, Oliveira Maria Fabiana Batista de, Santos Ricardo Cley Silvestre, Araújo Raquel Melo, Alves José Antonio Barreto, Pinheiro Kariny Souza, Gurgel Ricardo Queiroz, Mussi-Pinhata Marisa Márcia
Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP.
Rev Soc Bras Med Trop. 2009 Sep-Oct;42(5):532-6. doi: 10.1590/s0037-86822009000500010.
The seroprevalence of antibodies for HIV, syphilis, toxoplasmosis, cytomegalovirosis and rubella and its association with age and origin was investigated among pregnant women in Sergipe, northeastern Brazil. A total of 9,550 pregnant women (2,112 from the state capital and 7,438 from other municipalities) were enrolled in the study and consecutively tested during their first antenatal care visit in 2007. The following serum prevalences were found: syphilis (0.9%; 95% CI 0.7%-1.6%), HIV (0.14%; 95% CI 0.08%-0.2%), toxoplasmosis (IgG 69.3%; 95% CI 68.3%-70.2%; IgM 0.4%, 95% CI 0.3%-0.6%), cytomegalovirosis (IgG 76.6%, 95% CI 75.7%-77.5%; IgM 0.2%, 95% CI 0.09%-0.3%) and rubella (IgG 71.6%, 95% CI 70.7%-72.6%; IgM 0.1%, 95% CI 0.04%-0.2%). Toxoplasmosis seropositivity increased with age. The prevalences of IgG antibodies for toxoplasmosis, cytomegalovirus and rubella were higher in Aracaju (state capital) than in other municipalities in the State of Sergipe. The results showed that a large proportion of the pregnant women, particularly in municipalities other than the state capital, were susceptible to toxoplasmosis, rubella and cytomegalovirus, with a risk for their infants.
在巴西东北部塞尔希培州的孕妇中，对人类免疫缺陷病毒（HIV）、梅毒、弓形虫病、巨细胞病毒病和风疹抗体的血清流行率及其与年龄和籍贯的关系进行了调查。共有9550名孕妇（2112名来自州首府，7438名来自其他市镇）纳入本研究，并于2007年在她们首次产前检查时连续进行检测。发现以下血清流行率：梅毒（0.9%；95%置信区间0.7%-1.6%）、HIV（0.14%；95%置信区间0.08%-0.2%）、弓形虫病（IgG 69.3%；95%置信区间68.3%-70.2%；IgM 0.4%，95%置信区间0.3%-0.6%）、巨细胞病毒病（IgG 76.6%，95%置信区间75.7%-77.5%；IgM 0.2%，95%置信区间0.09%-0.3%）和风疹（IgG 71.6%，95%置信区间70.7%-72.6%；IgM 0.1%，95%置信区间0.04%-0.2%）。弓形虫病血清阳性率随年龄增加。在阿拉卡茹（州首府），弓形虫病、巨细胞病毒和风疹IgG抗体的流行率高于塞尔希培州的其他市镇。结果表明，很大一部分孕妇，尤其是州首府以外市镇的孕妇，易感染弓形虫病、风疹和巨细胞病毒，其婴儿有感染风险。
