[系统性红斑狼疮与补体系统]
[Systemic lupus erythematosus and the complement system].
作者信息
Kaliterna Dusanka Martinović, Vergles Jadranka Morović, Radić Mislav
机构信息
Odsjek za klinicku imunologiju i reumatologiju, Klinika za unutarnje bolesti Klinicki bolnicki centar Split, Soltanska 1, 21000 Split.
出版信息
Reumatizam. 2009;56(2):26-8.
The complement system has important protective functions in both, the innate and the adoptive immune systems. Dysregulation of complement system can cause the tissue damage. The complement deficiency predispose to an infection, and also to a development of auto-immune diseases, especially systemic lupus erythematosus (SLE). The complement play an important role in the pathogenesis of SLE, and besides that the lower levels of complement's compounds are well recognised as marker of SLE activity and also the activity of secondary APS.
补体系统在固有免疫系统和适应性免疫系统中均具有重要的保护功能。补体系统失调可导致组织损伤。补体缺乏易引发感染，也易导致自身免疫性疾病的发生，尤其是系统性红斑狼疮（SLE）。补体在SLE的发病机制中起重要作用，此外，补体成分水平降低是SLE活动以及继发性抗磷脂综合征（APS）活动的公认标志物。
Zotero 插件