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儿童门静脉高压症的脾动脉栓塞术

Splenic artery embolisation for portal hypertension in children.

作者信息

Meisheri Ila V, Kothari Paras R, Kumar Anil, Deshmukh A

机构信息

Department of Paediatric Surgery, B. J. Wadia Children Hospital, India.

出版信息

Afr J Paediatr Surg. 2010 May-Aug;7(2):86-91. doi: 10.4103/0189-6725.62854.

Abstract

BACKGROUND

Bleeding from esophageal varices is one of the most common causes of serious gastrointestinal haemorrhage in children. We analysed our experience with the use of splenic artery embolisation and variceal sclerotherapy for bleeding oesophageal varices.

PATIENTS AND METHODS

Records of all patients treated for bleeding oesophageal varices caused by portal hypertension from 1998 to 2004 were retrospectively analysed. Patients were followed up for five years.

RESULTS

Out of 25 patients treated, ten belonged to sclerotherapy (group A), eight to combined sclerotherapy and embolisation (group B), and seven to only embolisation (group C). The patients were selected randomly, only two patients who had active bleed recently were directly sclerosed. The splenic artery was embolised at the hilum using steel coils in 15 patients with portal hypertension and hypersplenism. Follow-up findings showed decrease in splenic mass, varices, and hyperdynamic flow.

CONCLUSION

In spite of few patients and a short period of follow-up, our results pointed out that a serious consideration should be given to this procedure, as it slowed the sequel of portal hypertension and the complications associated with it. Patients who were embolised and followed up for five years had lesser rebleeds and complications than sclerotherapy patients.

摘要

背景

食管静脉曲张出血是儿童严重胃肠道出血的最常见原因之一。我们分析了使用脾动脉栓塞术和曲张静脉硬化疗法治疗食管静脉曲张出血的经验。

患者与方法

回顾性分析1998年至2004年所有因门静脉高压导致食管静脉曲张出血而接受治疗的患者的记录。对患者进行了为期五年的随访。

结果

在接受治疗的25例患者中,10例接受硬化疗法(A组),8例接受硬化疗法与栓塞术联合治疗(B组),7例仅接受栓塞术(C组)。患者是随机选择的,只有2例近期有活动性出血的患者直接接受了硬化治疗。15例门静脉高压和脾功能亢进患者在脾门处使用钢圈栓塞脾动脉。随访结果显示脾脏体积、静脉曲张和高动力血流减少。

结论

尽管患者数量较少且随访时间较短,但我们的结果表明应认真考虑这一治疗方法,因为它减缓了门静脉高压的后遗症及其相关并发症。接受栓塞术并随访五年的患者比接受硬化疗法的患者再出血和并发症更少。

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