Riviera Veine Institut, 6, rue Gounod, 06000 Nice, France.
Eur J Vasc Endovasc Surg. 2010 Jul;40(1):122-8. doi: 10.1016/j.ejvs.2010.03.031.
To evaluate the effect of phlebectomy on venous reflux and diameter of the great saphenous vein (GSV).
Prospective cohort study.
Patients presenting with reflux in the GSV resulting in varicose veins were included in this series. Patients were treated by phlebectomy for dilated and incompetent tributaries of the GSV with conservation of the incompetent GSV. We measured reflux duration (RD), peak reflux velocity (PRV) and the diameter of the GSV using duplex ultrasound imaging at inclusion and 1 month after surgery.
We included 55 limbs in 54 patients (30 women and 24 men) aged from 37 to 83 (mean age 63) years.
Following treatment we observed a significant reduction of the mean RD (0.81 s vs. 1.5 s p < 0.01, t-test), mean PRV (120 mm s(-1) vs. 249 mm s(-1)p < 0.01, t-test) and mean diameter of the GSV (SFJ = 5.6 mm vs. 6.7 mm, p < 0.01, sub-terminal valve 4.8 mm vs. 4.4 mm p < 0.05, mid-thigh 5.0 mm vs. 4.2 mm, p < 0.01, knee 4.0 mm vs. 5.3 mm p < 0.01, mid-calf 2.7 mm vs. 4.0 mm, p < 0.01, t-test).
We noted reduced reflux in the GSV after phlebectomy with a significant reduction in RD and PRV. Phlebectomy also led to a significant reduction in GSV diameter. These data suggest that the haemodynamics and the diameter of the SV can be improved by using a treatment focussing on the saphenous tributaries.
评估静脉切除术对大隐静脉（GSV）静脉反流和直径的影响。
前瞻性队列研究。
本系列纳入了因 GSV 反流导致静脉曲张的患者。采用静脉切除术治疗 GSV 扩张和功能不全的属支，保留功能不全的 GSV。我们使用双功能超声成像在纳入时和手术后 1 个月测量反流持续时间（RD）、反流峰值速度（PRV）和 GSV 直径。
我们纳入了 54 例患者（30 名女性和 24 名男性）的 55 条肢体，年龄 37 至 83 岁（平均年龄 63 岁）。
治疗后，我们观察到平均 RD（0.81 秒 vs. 1.5 秒，p < 0.01，t 检验）、平均 PRV（120mm/s vs. 249mm/s，p < 0.01，t 检验）和 GSV 平均直径（SFJ = 5.6mm vs. 6.7mm，p < 0.01，t 检验）显著降低（SFJ = 5.6mm vs. 6.7mm，p < 0.01，t 检验）。
我们发现静脉切除术可减少 GSV 反流，RD 和 PRV 显著降低。静脉切除术还导致 GSV 直径显著缩小。这些数据表明，通过治疗重点关注隐静脉属支，可以改善 SV 的血液动力学和直径。
