外瓣膜成形术修复大隐静脉功能可减小静脉直径：多中心研究的 6 个月结果。
Functional repair of the great saphenous vein by external valvuloplasty reduces the vein's diameter: 6-month results of a multicentre study.
机构信息
Department of Vascular Surgery, St. Josef Hospital Bochum, Katholisches Klinikum Bochum Department of the Ruhr University Bochum, Bochum, Germany.
Vein Centre of the Departments of Dermatology and Vascular Surgery, Katholisches Klinikum Bochum, Bochum, Germany.
出版信息
J Int Med Res. 2021 May;49(5):3000605211014364. doi: 10.1177/03000605211014364.
OBJECTIVES
External valvuloplasty (eVP) is a reconstructive surgical method to repair the function of the terminal and preterminal valves. We evaluated the 6-month outcomes of eVP regarding the diameter of the great saphenous vein (GSV).
METHODS
Patients from five vein centres were included in this observational study. Follow-up involved detailed duplex sonography of the GSV. The venous clinical severity score (VCSS) and the C class of the clinical, aetiologic, anatomic and pathophysiologic (CEAP) classification were recorded.
RESULTS
We enrolled 210 patients, with a follow-up rate of 58%; eVP was sufficient in 95.24% of the patients. The GSV diameters decreased significantly from 4.4 mm (standard deviation (SD): 1.39) to 3.9 (SD: 1.12), 4 cm distal to the saphenofemoral junction (SFJ); from 3.7 mm (SD: 1.10) to 3.5 mm (SD: 1.02) at the mid-thigh; from 3.6 mm (SD: 1.14) to 3.3 mm (SD: 0.94) at the knee and from 3.1 mm (SD: 0.99) to 2.9 mm (SD: 0.78) at the mid-calf. VCSS decreased significantly from 4.76 (SD: 2.13) preoperatively to 1.77 (SD: 1.57) 6 months postoperatively.
CONCLUSIONS
GSV function can be restored by eVP; diameters over the total length of the GSV decreased significantly.
目的
外瓣膜成形术（eVP）是一种修复终末和近末端瓣膜功能的重建性外科方法。我们评估了 eVP 对大隐静脉（GSV）直径的 6 个月结果。
方法
本观察研究纳入了来自五个静脉中心的患者。随访包括 GSV 的详细双功能超声检查。记录静脉临床严重程度评分（VCSS）和临床、病因、解剖和病理生理（CEAP）分类的 C 级。
结果
我们共纳入 210 例患者，随访率为 58%；95.24%的患者 eVP 足够。GSV 直径从 SFJ 以下 4cm 处的 4.4mm（标准差（SD）：1.39）显著减小至 3.9（SD：1.12）；从大腿中部的 3.7mm（SD：1.10）减小至 3.5mm（SD：1.02）；从膝关节的 3.6mm（SD：1.14）减小至 3.3mm（SD：0.94）；从中腿的 3.1mm（SD：0.99）减小至 2.9mm（SD：0.78）。VCSS 从术前的 4.76（SD：2.13）显著降低至术后 6 个月的 1.77（SD：1.57）。
结论
eVP 可恢复 GSV 功能；GSV 的总长度上的直径显著减小。
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