Scottish Pulmonary Vascular Unit, Level 1 Regional Heart and Lung Centre, Golden Jubilee National Hospital, Beardmore Street, Glasgow G81 4HX, UK.
Thorax. 2010 May;65(5):454-5. doi: 10.1136/thx.2008.111955.
Supraventricular tachycardia (SVT) is a rare but important complication of pulmonary arterial hypertension. beta-Adrenoceptor blocking agents are commonly used to treat SVT, but they are potentially dangerous in the context of pulmonary arterial hypertension. Their negative inotropic and chronotropic effects are poorly tolerated in this condition, where cardiac reserve is compromised by a reduced and fixed stroke volume, and their administration can result in significant cardiorespiratory compromise. This is not a new discovery, but it is nonetheless poorly recognised in day-to-day clinical practice.
室上性心动过速（SVT）是肺动脉高压的一种罕见但重要的并发症。β-肾上腺素能受体阻滞剂常用于治疗 SVT，但在肺动脉高压的情况下，它们具有潜在的危险性。在这种情况下，由于心搏量减少和固定，心脏储备受到损害，因此它们的负性肌力和变时作用很难耐受，并且它们的给药会导致严重的心肺功能障碍。这并不是一个新发现，但在日常临床实践中仍然认识不足。
