Department of Occupational and Environmental Medicine, College of Medicine, Korea University, Ansan, Korea.
J Korean Med Sci. 2010 May;25(5):752-7. doi: 10.3346/jkms.2010.25.5.752. Epub 2010 Apr 22.
This study examined urinary cotinine levels and self-reported smoking among pregnant women in Korea and the factors associated with smoking during pregnancy. The subjects were selected from pregnant women who visited 30 randomly sampled obstetric clinics and prenatal care hospitals in Korea in 2006. Smoking status was determined by self-reporting and urinary cotinine measurement. A total of 1,090 self-administered questionnaires and 1,057 urine samples were analyzed. The percentage of smoking revealed by self-reporting was 0.55% (95% confidence interval [CI], 0.11-0.99) and that revealed by urinary cotinine measurement (>100 ng/mL) was 3.03% (95% CI, 1.99-4.06). The kappa coefficient of agreement between self-reported smoking status and urinary cotinine measurement was 0.20 (95% CI, 0.03-0.37). Multiple logistic regression analysis revealed that early gestational period, low educational level, and being married to a smoker were significant risk factors for smoking during pregnancy. Smoking among pregnant women in Korea is not negligible, and those who are concerned to maternal and child health should be aware of this possibility among pregnant women in countries with similar cultural background.
本研究旨在调查韩国孕妇的尿可替宁水平和自我报告的吸烟情况,以及与孕期吸烟相关的因素。研究对象选自 2006 年韩国 30 家随机抽取的妇产科诊所和产前保健医院的孕妇。通过自我报告和尿可替宁检测来确定吸烟状况。共分析了 1090 份自填式问卷和 1057 份尿液样本。自我报告的吸烟率为 0.55%(95%置信区间[CI],0.11-0.99),尿可替宁检测结果>100ng/ml 的吸烟率为 3.03%(95%CI,1.99-4.06)。自我报告的吸烟状况与尿可替宁检测结果之间的kappa 系数一致性为 0.20(95%CI,0.03-0.37)。多因素 logistic 回归分析显示,孕早期、低教育水平和与吸烟者结婚是孕期吸烟的显著危险因素。韩国孕妇的吸烟现象不容忽视,具有类似文化背景的国家中,那些关注母婴健康的人应该意识到这一可能性。